Ghrelin, a substance related to growth-hormone, is being studied to determine if it may improve the symptoms of emphysema. Ghrelin is known to stimulate muscle growth, create anti-inflammatory effects, promote dilation of blood vessels, and improve heart performance. Researchers hypothesized that use of the drug in emphysema patients might reduce lung inflammation and remodeling and might also improve lung mechanics and cardiac function.

Results of a Study Using Ghrelin to Treat Emphysema Symptoms in Mice

In a study using mice in which lung damage was caused by introducing chemicals into the lungs to cause emphysema, ghrelin was found to reduce the lung damage, improve heart function, and also increase muscle mass.

The researchers concluded that the results achieved by this study should prompt further studies to evaluate ghrelin as a potential therapy for emphysema.  However, drugs that work in mice often do not work the same way in people.  Extensive testing in patients would be required to prove the value of this therapy.

Information for this article was obtained from BioMed Central.

A New Drug May Improve Lung and Cardiovascular Function
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6 thoughts on “A New Drug May Improve Lung and Cardiovascular Function

  • May 31, 2018 at 8:11 am
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    I would love to be a study for this new medication, it may not help me but it could possibly help someone else in the future.

    Reply
    • June 27, 2018 at 6:45 am
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      That is commendable, Margaret. Unfortunately, there is no immediate testing with humans scheduled at this time that we know of, but if this developed, we would post the information here on this blog.

      Reply
  • June 1, 2018 at 10:40 am
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    How would one go about being in a trial for this?

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    • June 27, 2018 at 6:44 am
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      Thank you for writing, Vickie. You’re not the first to ask how to participate in a trial for ghrelin! While the research we reported on is encouraging, unfortunately, as stated in this article, “drugs that work in mice often do not work the same way in people.” There is no immediate testing with humans scheduled at this time that we know of, but if this developed, we would post the information here on this blog.

      Reply
  • June 5, 2018 at 2:55 pm
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    I think that is wonderful news. How long would the studies be on humans? I would love to try it. I would try anything. This COPD is nasty.

    Reply
    • June 27, 2018 at 6:41 am
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      It is indeed encouraging news, but unfortunately, as stated in this article, “drugs that work in mice often do not work the same way in people. Extensive testing in patients would be required to prove the value of this therapy.” There is no immediate testing with humans scheduled at this time that we know of, but if this developed, we would post the information here on this blog.

      Reply

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